Synthesis, spectroscopic characterization, conductivity and biological studies of some transition metals ions complexes and their nanocoordinated complexes of some novel Schiff base ligands derived from sulphachloropyrazine with some aldehydes.

Abstract

The present thesis includes five chapters and the contents are subdivided into introduction, experimental as well as results and discussion. Chapter I: This chapter includes a literature survey for the important studies of Schiff base ligands, their metal complexes, nanoparticles and nanocoordination chemistry. Chapter II: This chapter includes a detailed account about the experimental procedures and methods of preparation of Schiff base ligands and their complexes with metal ions [Co(II), Ni(II), Cu(II), Zn(II) and Cd(II)], also preparation of Cu nanocomplexes. Finally the working procedures and the apparatus (molar conductance, IR, 1H-NMR, UV-Vis, ESR, magnetic susceptibility TGA – DrTGA, Transmission electron microscope image (TEM), X-ray diffraction (XRD) biological, anticancer activity, DNA cleavage, Molecular docking, Molecular modeling , Electrical conductivity) are discussed.