MR imaging of Lesions of the corpus callosum in adults and children

Abstract

Being the largest brain commissure, the corpus callosum is related to cognitive functions, social skills, problem solving, and attention. Thanks to its multiplanar nature and high tissue resolution magnetic resonance imaging is a method of choice in the assessment of the corpus callosum and its congenital and acquired pathological lesions. It is a perfect diagnosing tool from the very beginning of life, that is, from the prenatal period. Visualization of callosal involvement helps to establish diagnosis in certain disease entities. The pathology of the corpus callosum includes a wide variety of entities that arise from different causes such as congenital, inflammatory, tumoral, degenerative, infectious, metabolic, traumatic, vascular and toxic agents. The corpus callosum, or a specific part of it, can be affected selectively. Our study involved 73 patients (37 male and 36 female) with age range 1 day-78 years. Our data and in agreement with the previous studies has demonstrated that MRI is a valuable diagnostic tool for patients with corpus callosal lesions , utilizing contrast enhanced sequences as well as new MRI sequences such as Cube FLAIR , Spectroscopy , DTI and CSF flowmetry sequences . MRI has also