A Comparative Study Between Preoperative Subconjunctival Bevacizumab Injection And Postoperative Topical Application In Prevention Of Recurrence After Excision Of Primary Pterygium In Egyptian Patients

Abstract

Pterygium is a growth of fleshy fibrovasculr tissue from the conjunctiva starts usually nasally and extends onto corneal surface. It may remain small and atrophic or could be fleshy and vascular and grows progressively to cover part of the cornea up to the pupil so it can mask the vision and/or distort the corneal surface making corneal astigmatism. There is no definite cause to its occurrence ,but there are multiple risk factors can lead to it e.g eye dryness, excess exposure to ultraviolet rays, ,dust and humidity so it is mostly seen in people who spend a lot of time in such circumstances like farmers, soliders, bakers… etc. Different studies were done searching for methods to prevent the occurrence of such recurrence ;some of them applied different surgery techniques like; simple excision and leaving bare sclera or doing conjunctival autograft at the site of excised pterygium. Others discovered that usage of certain drugs like Mitomycin C or Anti VEGFs like Bevacizumab (Avastin) could be helpful in prevention of recurrence.