Effect of Follicular Fluid Lactoferrin level on Oocytes Quality and Pregnancy rate in Intracytoplasmic Sperm Injection Cycles

Abstract

Placing the human ovum with spermatozoa outside the women and transferring the resulting embryo to her uterus is a relatively rapidly evolving approach to overcome human fertility problems. The first reports of implantation and pregnancy following the use of this technique in human were published during the 1978. Since then, the techniques known as in vitro fertilization (IVF) and embryo transfer (ET), have resulted in new insights into gamete interactions and early embryonic development, as well as numerous pregnancies. However, IVF tends to be less successful for the treatment of male factor infertility than the treatment of tubal factor infertility (Tourney et al., 1992). Intracytoplasmic sperm injection (ICSI) is now one of the most successful and viable techniques in assisted fertilization (Nagy et al., 1995). In those who have no identifiable or correctable causes, ICSI provides new hope for infertility (Chow et al., 2006). Human oocyte maturation is considered as the reinitiation and completion of the first meiotic division from