Click and Release: SO2 Prodrugs with Tunable Release Rates

Serya, Rabah; Khaled A.M.abouzid; Deena S.Lasheen; Xingyue Ji; Binghe Wang; Khaled A M Abouzid;

Abstract


Employing an intramolecular cycloaddition reaction, we have developed a series of SO2 prodrugs with tunable release rates with half lives ranging from minutes to days.


Other data

Title Click and Release: SO2 Prodrugs with Tunable Release Rates
Authors Serya, Rabah ; Khaled A.M.abouzid; Deena S.Lasheen; Xingyue Ji; Binghe Wang; Khaled A M Abouzid 
Keywords Thiophenes,Hydrocarbons,Cyclization,Addition reactions,Pharmaceuticals
Issue Date 30-Jan-2017
Publisher American chemical society
Journal Organic Letters 
Volume 19
Start page 818
DOI org/10.1021/acs.orglett.6b03805

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