Serum α-klotho levels are not informative for the evaluation of growth hormone secretion in short children
Meazza, Cristina; Khalaf, Randa I; Lupi, Fiorenzo; Pagani, Sara; El Kholy, Mohamed; Tinelli, Carmine; Radetti, Giorgio; Bozzola, Mauro; Elsedfy, Heba;
Abstract
α-Klotho is a transmembrane protein that can be cleaved and act as a circulating hormone (s-klotho). s-Klotho serum levels seem to reflect growth hormone (GH) secretory status. We investigated the role of s-klotho as a reliable marker of GH secretion in short children and the factors influencing its secretion.
Other data
| Title | Serum α-klotho levels are not informative for the evaluation of growth hormone secretion in short children | Authors | Meazza, Cristina; Khalaf, Randa I; Lupi, Fiorenzo; Pagani, Sara; El Kholy, Mohamed ; Tinelli, Carmine; Radetti, Giorgio; Bozzola, Mauro; Elsedfy, Heba | Keywords | children;growth hormone (GH) deficiency diagnosis;IGF-I;klotho | Issue Date | 26-Oct-2017 | Publisher | WALTER DE GRUYTER GMBH | Journal | Journal of Pediatric Endocrinology and Metabolism | Volume | 30 | Issue | 10 | ISSN | 0334-018X | DOI | 10.1515/jpem-2016-0464 | PubMed ID | 28902627 | Scopus ID | 2-s2.0-85030988083 | Web of science ID | WOS:000412132400006 |
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