Utility of cyano-N-(2-oxo-1,2-dihydroindol-3-ylidene)acetohydrazide in the synthesis of novel heterocycles
Mahmoud, Mahmoud R.; El-Ziaty, Ahmed K.; Abu El-Azm, Fatma; Ismail, Mahmoud; Shibab, Sayed A.;
Abstract
Cyano-N-(2-oxo-1,2-dihydroindol-3-ylidene)acetohydrazide was prepared by condensation of isatin with cyanoacetohydrazide in refluxing 1,4-dioxane. Subsequent reaction with a variety of electrophilic and nucleophilic reagents afforded novel heterocyclic compounds and spirooxoindoles. The IR, 1H NMR and mass spectra of all the synthesised compounds are discussed.
Other data
| Title | Utility of cyano-N-(2-oxo-1,2-dihydroindol-3-ylidene)acetohydrazide in the synthesis of novel heterocycles | Authors | Mahmoud, Mahmoud R. ; El-Ziaty, Ahmed K.; Abu El-Azm, Fatma ; Ismail, Mahmoud ; Shibab, Sayed A. | Keywords | Isatin;Spirooxoindoles;Thiazole and coumarin derivatives | Issue Date | 1-Feb-2013 | Publisher | SAGE PUBLICATIONS LTD | Journal | Journal of Chemical Research | Volume | 37 | Issue | 2 | ISSN | 17475198 | DOI | 10.3184/174751912X13567100793191 | Scopus ID | 2-s2.0-84875493341 | Web of science ID | WOS:000316979100005 |
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