Synthesis and antimicrobial evaluation of some novel dithiolane, thiophene, coumarin, and 2-pyridone derivatives
Mahmoud, MR; Abu El-Azm, Fatma; Ali, AT; Ali, YM;
Abstract
Novel 2-cyano-N-[1-(naphtha-2-yl)ethylidene] acetohydrazide 1 was utilized as key intermediate for the synthesis of some new dithiolane, thiophene, coumarin, 2-pyridone, and other related products containing a hydrazide moiety. Newly synthesized compounds were characterized by elemental analyses and spectral data (IR, 1H NMR and mass spectra). The antimicrobial activity of the synthesized compounds was evaluated.
Other data
| Title | Synthesis and antimicrobial evaluation of some novel dithiolane, thiophene, coumarin, and 2-pyridone derivatives | Authors | Mahmoud, MR ; Abu El-Azm, Fatma ; Ali, AT; Ali, YM | Keywords | Cyanoacetohydrazide;dithiolane derivatives;hydrazide-hydrazone;thiophene derivatives;STRUCTURE-BASED DESIGN;BIOLOGICAL EVALUATION;2-PYRIDONE-CONTAINING PEPTIDOMIMETICS;AGENTS;INHIBITORS;1,3,4-THIADIAZOLES;NAPHTHALENE;HYDRAZONES;SPECTRA;ANALOGS | Issue Date | 2017 | Publisher | TAYLOR & FRANCIS INC | Journal | Synthetic Communications | Volume | 47 | Issue | 17 | Start page | 1591 | End page | 1600 | ISSN | 0039-7911 | DOI | 10.1080/00397911.2017.1336776 | Scopus ID | 2-s2.0-85021867154 | Web of science ID | WOS:000411384400006 |
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