Synthesis, Antiproliferative activity, and apoptotic profile of New Derivatives from the Meta Stable Benzoxazinone Scaffold

El-Sayed, Amira; El-Hashash, Maher; El-Sayed, Wael;

Abstract


Cancer exerts a huge strain on the health system. The emerging resistance to the current chemotherapies demands the continuous development of new anticancer agents with lower cost, higher efficacy, and greater specificity.


Other data

Title Synthesis, Antiproliferative activity, and apoptotic profile of New Derivatives from the Meta Stable Benzoxazinone Scaffold
Authors El-Sayed, Amira; El-Hashash, Maher; El-Sayed, Wael 
Keywords Quinazolinone;apoptosis;caspase;cell cycle;p53;regiospecificity;topoisomerase
Issue Date 6-Jul-2021
Journal Anti-Cancer Agents in Medicinal Chemistry 
ISSN 18715206
DOI 10.2174/1871520621666210706152632
PubMed ID 34229594

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