Utility of 3-(thiophen-2-yl)prop-2-enoyl isothiocyanate in heterocyclic synthesis

El-Hag, Amira; Saad R Atta-Allah; Magdy M Hemda;

Abstract


Convenient syntheses of quinazoline, benzothiazole, thiadiazole, imidazole, and thiourea derivatives starting from
3-(thiophen-2-yl)prop-2-enoyl isothiocyanate are described. The structures of the synthesized compounds are confirmed
from their microanalytical and spectral data. Some of the products are examined for their antibacterial activity against
Gram-positive and Gram-negative bacteria and fungi.


Other data

Title Utility of 3-(thiophen-2-yl)prop-2-enoyl isothiocyanate in heterocyclic synthesis
Authors El-Hag, Amira ; Saad R Atta-Allah; Magdy M Hemda
Issue Date 15-Jun-2019
Journal JOURNAL OF CHEMICAL RESEARCH 
Volume 43
Start page 307
End page 312
DOI 10.1177/1747519819862176

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