Use of Phthalimidoacetyl isothiocyanate as a Scaffold in Synthesis of Target Heterocyclic Systems with Their Antimicrobial Assessment
Magdy Mohamed Hemdan; El-Hag, Amira;
Abstract
Phthalimidoacetyl isothiocyanate underwent addition-cyclization reactions with some nitrogen and carbon
nucleophilic reagents. Simultaneous or subsequent cyclization of the obtained adducts gave target heterocyclic
systems such as 1,2,4-triazoles, 1,3-diazines, 1,3-oxazines and thiourea attached to a phthalimido
moiety. The antimicrobial activity of the synthesized compounds was tested.
nucleophilic reagents. Simultaneous or subsequent cyclization of the obtained adducts gave target heterocyclic
systems such as 1,2,4-triazoles, 1,3-diazines, 1,3-oxazines and thiourea attached to a phthalimido
moiety. The antimicrobial activity of the synthesized compounds was tested.
Other data
| Title | Use of Phthalimidoacetyl isothiocyanate as a Scaffold in Synthesis of Target Heterocyclic Systems with Their Antimicrobial Assessment | Authors | Magdy Mohamed Hemdan; El-Hag, Amira | Issue Date | 17-Feb-2016 | Journal | Chem. Pharm. Bull. | Volume | 64 | Issue | 5 | Start page | 483 | End page | 489 | DOI | https://doi.org/10.1248/cpb.c16-00099 |
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