Long term follow up of patients with low grade chondrosarcoma in the appendicular skeleton treated by extended curettage and liquid nitrogen

Abstract

Chondrosarcoma is the second most common sarcoma of bone, accounting for about 25% of primary bone tumors. Histological grading is the single most important determinant of local recurrence and metastases, where low grade chondrosarcoma (grade 1: atypical cartilaginous lesion) is associated with 10 years survival rate 79-100%. There has been always a debate about the need for wide resection in managing low grade chondrosarcoma, where several reports describe successful management with extended curettage and adjuvant therapy, minimizing the need for complex reconstructive procedures and improving the expected outcomes.