Structure-based molecular design, synthesis, and in vivo anti-inflammatory activity of pyridazinone derivatives as nonclassic COX-2 inhibitors

Abouzid, Khaled; Khalil, NA; Ahmed, E.M.; El-Latif, HAA; El-Araby, ME;

Other data

Title Structure-based molecular design, synthesis, and in vivo anti-inflammatory activity of pyridazinone derivatives as nonclassic COX-2 inhibitors
Authors Abouzid, Khaled ; Khalil, NA; Ahmed, E.M. ; El-Latif, HAA; El-Araby, ME
Keywords Quinoxaline;Pyridazinone;Anti-inflammatory;Molecular design;Synthesis;SELECTIVE CYCLOOXYGENASE-2 INHIBITORS;COLORECTAL-CANCER PREVENTION;BIOLOGICAL EVALUATION;AGENTS;EXPRESSION;SERIES;DRUGS
Issue Date 2010
Publisher SPRINGER BIRKHAUSER
Journal Medicinal Chemistry Research 
Volume 19
Start page 629
End page 642
ISSN 1054-2523
DOI 10.1007/s00044-009-9218-4
Web of science ID WOS:000280557700002

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Structure-based molecular design, synthesis, and in vivo anti-inflammatory activity of pyridazinone derivatives as nonclassic COX-2 inhibitors


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