Predictors of Contrast induced Nephropathy Following Percutaneous Coronary Intervention in Patients with Chronic Total Occlusion

Abstract

C ontrast induced nephropathy (CIN) is one of the agreed upon complications of procedures that foresee the use of contrast media, recognized as a leading cause of morbidity and mortality in patients undergoing percutaneous coronary intervention (PCI) and is commonly defined as an increase in serum creatinine levels; usually 0.5 mg/dl or 25% of baseline levels, within 24–48h after contrast exposure. The aim of the work is to predict the development of contrast induced nephropathy in patients undergoing chronic total occlusion after per-cutaneous coronary intervention. This study is a prospective observational study, the sample was taken consecutively. The study data was obtained from all subjects who were admitted to Ain Shams affiliated hospitals, Cairo, Egypt, conducted in a prospective consecutive manner in our hospital over period of 6 months commencing in June 2021. The study is approved through FMASU REC which is organized and operated to guidelines of the inter- national council on Harmonization(ICH) and the Islamic organization for medical sciences (IOMS), The united states office for human research protections and the united code of federal regulations and operates under federal wide assurance no. FWA 000017585.