SYNTHESIS OF DIPICOLINIC ACID DERIVATIVES OF EXPECTED BIOLOGICAL ACTIVITY
ABD EL-GALIL E.A. AMR;
Abstract
SUMMARY
1. The thesis startes with an introduction covering a general review for the chemistry of 2,6-pyridinedicarboxylic acid (dipicolinic acid) till 1997. It includes also a special part presenting the obtained results followed by the experimental part and ended with a list of 280 references.
2. The thesis includes a course of investigation to synthesize a series of some peptide derivatives. Coupling of 2,6-pyridine dipicolinoyl dichloride (23) with amino acid methyl esters to afford 2,6-bis• (aminocarbonyl)pyridine methyl ester derivatives (125) was preformed followed by treating with hydrazine hydrate to give the corresponding dihydrazide derivatives (126).
1. The thesis startes with an introduction covering a general review for the chemistry of 2,6-pyridinedicarboxylic acid (dipicolinic acid) till 1997. It includes also a special part presenting the obtained results followed by the experimental part and ended with a list of 280 references.
2. The thesis includes a course of investigation to synthesize a series of some peptide derivatives. Coupling of 2,6-pyridine dipicolinoyl dichloride (23) with amino acid methyl esters to afford 2,6-bis• (aminocarbonyl)pyridine methyl ester derivatives (125) was preformed followed by treating with hydrazine hydrate to give the corresponding dihydrazide derivatives (126).
Other data
| Title | SYNTHESIS OF DIPICOLINIC ACID DERIVATIVES OF EXPECTED BIOLOGICAL ACTIVITY | Other Titles | تشييد بعض مشتقات حمض الداى بيكولينيك ذات فاعلية بيولوجية متوقعة | Authors | ABD EL-GALIL E.A. AMR | Issue Date | 1998 |
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