Role of MRI in diagnosis of prostate cancer and correlation of results with Trans rectal Ultrasound “TRUS” biopsy

Abstract

SUMMARY The prostate is an exocrine gland composed of both glandular and non-glandular tissue. It is a cone-shaped organ encircling the neck of bladder and urethra with the apex located immediately above the urogenital diaphragm and the broad base below the bladder (Kim B. & Kim C.K, 2013). Prostate cancer is the most common non cutaneous cancer in elderly men, and the second leading cause of cancer-related death in developed countries. (Zidan S, et al,2015) Although most types of prostate cancer grow slowly and may need minimal treatment, other types are aggressive and can spread quickly. Prostate cancer that is detected early has a better chance of successful treatment. Therefore, detection of prostate cancer in an early stage is important but remains challenging (Jemal et al. 2012). Localization of prostate cancer is an important given in the emergence of disease-targeted therapies. Knowledge of the lesion location within the prostate can help to direct maximal therapy to the largest focus of tumor while minimizing damage to the surrounding structures, such as the neurovascular bundles, the rectal wall and the bladder neck (Haider et al , 2007)