CLINICOPATHOLOGICAL STUDIES ON BLOOD BABESIASIS WITH TBIALS OF TREATMENT IN CATTLE

Abstract

SUMMARY The present study was carried out to investigate the haematological and biochemical changes due to infection with B.bigemina in cattle and to evaluate the response of these changes for treatment either by Imizol or Berenil. In addition to use IFAT as serological method for diagnosis and monitoring antibodies titre in serum of infected cattle before and after treatment. Thirty male, native breed cattle aged 12: 14 months were used and classified into two main groups: a) Group (c): Consists of 10 animals which proved to be non infected with B.bigemina and served as a control healthy. b) Group (N): Consists of 20 animals suffering from babesiasis which characterized clinically by fever, anorexia, weakness and hemoglobinuria. Laboratory examination of the blood smears revealed that diseased animals infected with B.bigemina. This group divided for treatment into two subgroups: 1. Subgroup (TI): consists of 10 animals that treated by therapeutic dose oflmizol. 2. Subgroup (TB): Consists of 10 animals that treated by therapeutic dose of Berenil. Blood samples were collected from healthy and infected animals from Jugular vein and also collected from infected animals that treated with Imizol and Berenil two days, one week and two weeks post treatment. Two blood samples were taken from each animal, the first -85- sample collected on EDTA and examined haematologically and the second sample collected in a centrifuge tube, left for serum separation to perform the biochemical analysis.