ESMOLOL, FENTANYL, LIDOCAINE IN ATTENUATION OF HEMODYNAMIC RESPONSE TO TRACHEAL INTUBATION IN OLD PATIENTS

Abstract

This study was carried out in EL-Minia University hospital on eighty patients of both sex who were scheduled for different eleclive surgical procedures that would require tracheal intubation in order to investigate the hemodynamic response following laryngoscopy and tracheal intubation and to compare the effects of intravenous lidocaine fentanyl and esmolol on altenuating these responses All patients were premedicated with intravenous mi dazol am C5mg) before induction ofanaest.hesia with thiopenlal sodium (4-5mg/kg), then the studying drug which was used t-o attenuate the hemodynamic response to laryngoscopy and intubalion was given. Succinylcholine was given in a dose of 1mg/kg to facilitate endotracheal intubation which was performed in 15-30 seconds. Anaesthesia was maintained with nitrous oxide oxygen ( 6 : 4) and halothane 1-1. 5%. No other drugs was (given during the period of the study (the first 10 minutes). According to the drug used to attenuate hemodynamic responses to laryngoscopy and endotracheal intubalion the patients were divided into Group I (Control Group) . Members of this lour groups each oi 20 patients : group were received placebo CdeA rose 5%) 90 seconds before intubation. Group II (Lidocaine Group) :- Subjects of this group were received intravenous lidocaine 1.5mg/kg as in group I.