The Effect of Injectable Platelet Rich Fibrin ( I-PRF) with Bone Graft and Leukocyte Platelet Rich Fibrin(L-PRF) Membrane in The treatment of Localized Gingival Recession (Randomized Controlled Clinical and Tomographic Study)

Abstract

Gingival recession is one of the most common esthetic problems facing patients. Gingival recession had several classifications throughout dental literature; the most commonly used classification is Miller’s classification which was introduced in 1985. Several modifications were proposed to it as its major drawbacks were the inability to specify and identify the mucogingival junction, keratinized tissue amount and inability to determine the amount of interdental bone loss. There are a lot of techniques for treatment of gingival recession that include different surgical flaps with or without grafting. The most commonly used treatment for gingival recession is the coronally repositioned flap with or without soft tissue grafting. The most commonly used graft for recession treatment is the sub epithelial connective tissue graft which is the gold standard as it is able to achieve complete root coverage and increase in the gingival tissue thickness. Recently other grafting options were introduced: Alloderm, guided tissue membranes with and without bone grafting beneath them and Platelet Rich Fibrin (PRF) and its derivatives. Platelet Rich Fibrin is one of the platelet concentrates that was introduced by Choukron in 2001, it provide the tissues with growth factors and stimulate angiogenesis and wound healing. There are different preparations of PRF which are: leucocyte platelet rich fibrin (L-PRF), advanced platelet Rich Fibrin (a-PRF) and injectable platelet Rich Fibrin (i-PRF), these preparations are rich in growth factors. i-PRF is an