Foley's Catheter with or without Misoprostol in Induction of labor: (Randomised Double Blind Control Study)

Abstract

his randomized double blind controlled study was aimed to compare the efficacy of the use of foley’s catheter with either misoprostol or placebo to improve induction to delivery interval in pregnant women with unfavorable cervix undergoing induction of labour on similar number of nullipara (25 case) and multipara (25 case) to be of total 50 patients in each group. The primary outcome was induction to delivery interval, while Secondary outcomes were uterine contractile abnormalities, mode of delivery, maternal and neonatal outcome, neonatal birth weight, Apgar score, any maternal or fetal complication and the amount of oxytocin used for induction Findings: No significant difference between the studied groups regarding demographic characteristics as age, BMI, GA & bishop score (p=0.238, 0.839, 0.490 &0.460 respectively). Oxytocin duration and total dose were significantly lower in combined group (6.6±1.6 & 9.8±4.1 respectively) than in Foley's group (8.8±1.6 &12.7.0±4.9 respectively) as p<0.001 &0.033 respectively. There was Non-significant difference between the studied groups regarding mode of delivery and indications of CS (p=0.480& 1.000 respectively). The majority of both group