Latest updates in the efficiency of the novel MRI technique Diffusion weighted imaging with background signal suppression (DWIBS) in comparison to dynamic contrast enhancing MRI technique in clarifying suspicious breast lesions.

Abstract

Being the most common invasive cancer affecting females world-wide; early detection and proper treatment of breast cancer has always taken a high priority in scientific researches world-wide. Despite the marked improvement in the screening tools, in many cases histo-pathology is usually required. This may be the result of relatively high false-positive results of screening tools such as mammography. Despite its role in the detection of bilateral/ multi-centric tumors, DCE-MRI has considerable percentage of high false positive results. Another reason is that DCE-MRI is not feasible in all cases such as in cases of renal impairment since the injection of gadolinium based contrast requires adequate renal functions to avoid more serious renal impairment. This has created a growing need for a sensitive and specific screening and diagnostic imaging technique without the need for contrast injection. Conventional DWI (diffusion weighted imaging) with ADC maps has been proposed to increase the specificity of