Relation between 25-Hydroxy Vitamin D Deficiency and Success of Cardioversion for Lone Atrial Fibrillation (AF)

Abstract

trial fibrillation (AF) is the most common serious abnormal heart rhythm and, as of 2020, affects more than 33 million people worldwide. It is associated with substantial morbidity and mortality and is an important risk factor for stroke and systemic embolism, it increases mortality rate caused by stroke to five times. Lone AF was meant to indicate AF in patients for whom subsequent investigations could not demonstrate heart disease. The prevalence of lone AF has fallen due to increasing knowledge about the pathophysiology of AF, which shows that in every patient a cause is present. However, subjects with lone AF provide a unique opportunity to eliminate the effects of associated conditions as many previous studies exploring inflammatory factors in AF have been confounded by concomitant medical illnesses. Rates of AF progression were significantly lower with rhythm control than rate control. The success rate of cardioversion depends on various patient characteristics as well as on some technical variables. In stable patients, either pharmacological cardioversion or electrical cardioversion can be attempted; pharmacological cardioversion is less effective but does not require sedation.