Does 1-Minute Walk Test Predict Results of 6- Minute Walk test in Patients with Interstitial Lung Diseases?

Abstract

T his prospective study held in Ain-shams university hospitals on thirty patient with ILD during the period between April 2019 and June 2019. ILD patients were included in this study if they had previous clinical features, documented high-resolution computed tomography (HRCT) scan findings and restrictive lung function pattern of ILD, and whom met an appropriate diagnostic ILD criteria in literature. The aim of the work was to investigate if one-minute walk test (1MWT) predicts the results of 6MWT test as regard the exercise capacity, exercise induced oxygen desaturation in patients with interstitial lung diseases (ILDs). The study design was approved by the research ethics committee of our institution and a written informed consent was obtained from each patient. All patients included underwent the following: full medical history, baseline physical examination, baseline spirometry, 1MWT and 6MWT. Spirometry was done as a baseline for all patients before one and six minute walking test. Forced expiratory volume in the first second (FEV1), forced vital capacity (FVC) and FEV1/FVC ratio were measured using the spirometry system (MIR spirolab III,SDI Diagnostics, Inc., Roma-Italy). Results were expressed in absolute values and as a percentage of normal predicted values according to the guidelines of the ATS/ERS.