Correlation between ADC Values and Split Renal Function by Renal Isotope Scan in Assessment of Nephropathy

Abstract

ephropathy is now a worldwide public health problem with rising incidence, it’s important to periodically assess the renal function for early detection and proper management of the patients. Serum markers as serum creatinine, BUN and e GFR only assess the global renal function. Intravenous urography, Ultrasonography and Computed tomography provides renal anatomical data but very little functional information. Renal scintigraphy provides excellent functional data, it can detect not only the global but also the individual/split GFR of each kidney, however this exam is very expensive, has low spatial resolution and utilizes ionizing radiation. Diffusion-weighted MRI (DW-MRI) is a non-invasive modality characterize tissues based on Brownian motion of water molecules within them. Our study aimed at introducing DW-MRI study as a potential radiological examination in detecting and evaluating the renal function, by correlating the ADC values calculated with the split GFR obtained from the dynamic renal scan that was used as a reference method.