Effect of Laparoscopic Ovarian Drilling on Outcomes of In-Vitro Fertilization in Clomiphene-Resistant Women with Polycystic Ovary Syndrome

Abstract

Polycystic ovary (PCO) is considered as one of the most common endocrine disorders. It occurs in 6-21% of women. It is the primary cause of an-ovulatory subfertility, accounting for at least 75% of cases with an-ovulatory subfertility. LOD has been proposed as an alternative to treatment of clomiphene-resistant patients with PCOS due to its quick and easy approach. A study has reported that the impact of LOD prior to ART is beneficial in decreasing the OHSS risk and improving the pregnancy rate in women with a history of cancellation of IVF cycle due to risk of OHSS. In this study we aimed to evaluate IVF/ICSI outcomes in clomiphene-resistant women with PCOS who were treated with LOD. The current study, included a total of 88 women with history of clomiphene-resistant PCOS, who had been distributed into two groups: a. Group A (N=44): clomiphene-resistant PCOS women who has history of LOD at least 6 months to 3 years before IVF/ICSI.