Clinical and Histologic Evaluation of Using Block Xenograft combined with Leukocyte/Platelet-Rich Fibrin (L-PRF) versus Intraoral Autogenous Bone Block Graft with L-PRF in Treating Localized Ridge Defect: A Randomized Clinical Trial

Abstract

Augmentation of alveolar ridge defects remains the cornerstone in tissue engineering. The amount and quality of alveolar bone available in all dimensions affects the success of dental implants for restoration of edentulous areas. Adequate and healthy bone supports degree of osseointegration which in turn affects the long term success of oral implants. Physiologic or pathologic bone loss is considered as a common clinical problem. Multiple causes may lead to this problem including periodontal diseases, teeth loss, trauma or using removal prosthesis for long periods. Excessive bone loss (more than 7 mm) leads to fixed prosthodontics lacking esthetic and function. Many biomaterials as well as surgical techniques were