The assessment of fibroblast growth factor 19 as a non-invasive serum marker for hepatocellular carcinoma

Hadeer Mohammed Fawzy;

Abstract


Liver cirrhosis represents the end stage of several chronic liver injuries. It is characterized by degeneration, regeneration by nodules with loss of lobular architecture, which results in decrease of liver cell mass, portal hypertension and porto-systemic shunt opening.

Hepatocellular carcinoma (HCC) represent the 5th common cancer worldwide and 3rd cause of death between cancers, which represent the most serious complication following chronic infection by hepatitis (C) virus and hepatitis (B) virus.

Tumor makers are widely used as a diagnostic follow up after treatment and prognosis. In HCC α fetoprotein (α FP) is used for diagnosis, follow up of HCC but with different variable changes so it cannot used alone as a biomarker of HCC.

Serum fibroblast growth factor 19 (FGF


Other data

Title The assessment of fibroblast growth factor 19 as a non-invasive serum marker for hepatocellular carcinoma
Other Titles تقييم عامل نمو الخلايا الليفية 19 كدلالة لسرطان الخلايا الكبدية
Authors Hadeer Mohammed Fawzy
Issue Date 2021

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