Utility of β-aroyl acrylic acid in heterocyclic synthesis
Rizk, Sameh Ahmed; El-Hashash, M. A.; Mostafa, K. K.;
Abstract
β-(4-bromobenzoyl) acrylic acid has been reacted with nitrogen nucleophiles namely ethanolamine and o-aminophenol and yielded the corresponding adduct la,b. On the other hand, ß-(3,4dichlorobenzoyl) acrylic acid has been reacted with carbon nucleophiles namely o-dichlorobenzene under Friedel-Crafts conditions and yielded the corresponding adduct Ic. Behaviour of compounds 1 toward hydrazine hydrate, hydroxylamine and acetic anhydride has been investigated. Acylation and alkylation of pyridazinone derivative also have been described.
Other data
| Title | Utility of β-aroyl acrylic acid in heterocyclic synthesis | Authors | Rizk, Sameh Ahmed ; El-Hashash, M. A.; Mostafa, K. K. | Keywords | β-(3,4-Dichloro and/or 4-bromobenzoyl) acrylic acid;Pyridazi-none and furanone | Issue Date | 1-Dec-2008 | Journal | Egyptian Journal of Chemistry | ISSN | 04492285 | Scopus ID | 2-s2.0-77952206806 |
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