Synthesis and utility of 6-(β-Phthalimidoethyl) -2-methyl and/or 2-phenyl-3, l-benzoxazin-4-ones in some heterocyclic synthesis

Abstract

The present work deals with synthesis of 3,1-benzoxazinone carrying a new functional group in position-6. The phthalimido group which has been applied as antipsychotic, anti-inflammatory agents and receptors. Hypolipidemic activity for phthalimide derivatives are important in medicinal chemistry and generation of different heterocycles; quinazolinone, triazole and pyrazoloquinazoline derivatives carry p-phthalimidoethyl group, via treatment of 3,1-benzoxazinones with nitrogen nucleophiles namely amines, hydrazine, ammonium acetate and hydrazide respectively. © 2012 IDOSI Publications.