Synthesis, reactions and application of chalcones: a systematic review

Shalaby, Mona A.; Rizk, Sameh Ahmed; Fahim, Asmaa M.;

Abstract


Chalcones are a group of naturally occurring compounds that have biological effects that include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone research, including their synthesis, structure-activity relationships, and biological activities, is summarized herein. Along with their toxicity and safety profiles, the prospective usage of chalcones in medicinal research and development is discussed. This review emphasizes the need for additional research in order to fully examine the therapeutic potential of chalcones as therapeutic agents for the treatment of a variety of disorders.


Other data

Title Synthesis, reactions and application of chalcones: a systematic review
Authors Shalaby, Mona A.; Rizk, Sameh Ahmed ; Fahim, Asmaa M.
Issue Date 8-Jun-2023
Journal Organic & biomolecular chemistry 
Volume 21
Issue 26
Start page 5317
End page 5346
ISSN 14770520
DOI 10.1039/d3ob00792h
PubMed ID 37338020
Scopus ID 2-s2.0-85163881118

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