Exploring the use of nanocarrier systems to deliver the magical molecule; Curcumin and its derivatives
Mehanny, Mina; Hathout, Rania M; Geneidi, Ahmed S.; Mansour, Samar;
Abstract
Curcumin and its derivatives; curcuminoids have been proven as potential remedies in different diseases. However, their delivery carries several challenges owing to their poor aqueous solubility, photodegradation, chemical instability, poor bioavailability and rapid metabolism. This review explores and criticizes the numerous attempts that were adopted through the years to entrap/encapsulate this valuable drug in nanocarriers aiming to reach its most appropriate and successful delivery system.
Other data
| Title | Exploring the use of nanocarrier systems to deliver the magical molecule; Curcumin and its derivatives | Authors | Mehanny, Mina ; Hathout, Rania M ; Geneidi, Ahmed S.; Mansour, Samar | Keywords | Curcumin;Curcuminoids;Drug delivery;Nanocarriers | Issue Date | 10-Mar-2016 | Journal | Journal of Controlled Release | Volume | 225 | Start page | 1 | End page | 30 | ISSN | 01683659 | DOI | 10.1016/j.jconrel.2016.01.018 | PubMed ID | 26778694 | Scopus ID | 2-s2.0-84955515803 |
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