Fabrication of sustainable hydrogels-based chitosan Schiff base and their potential applications
Kandile, Nadia; Taghreed H. Abdalla; Abir S. Nasr; Ghada Bassioni; David R. Harding;
Abstract
Chemical modifications of chitosan were of interest to scientific researchers for its wide
applications. Chitosan has been widely used for synthesis of unique compounds with potential bio logical activity and also effective for wastewater treatment. In the current study fabrication of new
chitosan-based Schiff base hydrogels were fabricated through modification of chitosan with isoni cotinic aldehyde to give hydrogel I or with epichlorohydrin or sodium tripolyphosphate via iono tropic gelation processes under the same reaction conditions to give hydrogels Ie, and
nanohydrogels II, IIe respectively. FTIR, XRD, TGA, DSC, SEM, and TEM tools were used
for characterization of the fabricated hydrogels I, Ie, II, and IIe hydrogels. The swelling behavior
of the fabricated hydrogels in different solvents were determined. Evaluation of the hydrogels for
leaching metal ions and biological activity towards different Gram-positive and Gram-negative
of microorganisms were studied. The results showed that the highest efficiency for adsorption of
cobalt and mercuric ions was revealed for hydrogels Ie, IIe (91.3%, 95.9%) and (92.5%, 95.9%)
respectively. However, hydrogel IIe showed remarkable MIC and MBC towards Gram-positive
(B. subtilis) (19.5, 38) lg/ml compared to the standard antibiotic Ciprofloxacin (19, 38) lg/ml
respectively.
applications. Chitosan has been widely used for synthesis of unique compounds with potential bio logical activity and also effective for wastewater treatment. In the current study fabrication of new
chitosan-based Schiff base hydrogels were fabricated through modification of chitosan with isoni cotinic aldehyde to give hydrogel I or with epichlorohydrin or sodium tripolyphosphate via iono tropic gelation processes under the same reaction conditions to give hydrogels Ie, and
nanohydrogels II, IIe respectively. FTIR, XRD, TGA, DSC, SEM, and TEM tools were used
for characterization of the fabricated hydrogels I, Ie, II, and IIe hydrogels. The swelling behavior
of the fabricated hydrogels in different solvents were determined. Evaluation of the hydrogels for
leaching metal ions and biological activity towards different Gram-positive and Gram-negative
of microorganisms were studied. The results showed that the highest efficiency for adsorption of
cobalt and mercuric ions was revealed for hydrogels Ie, IIe (91.3%, 95.9%) and (92.5%, 95.9%)
respectively. However, hydrogel IIe showed remarkable MIC and MBC towards Gram-positive
(B. subtilis) (19.5, 38) lg/ml compared to the standard antibiotic Ciprofloxacin (19, 38) lg/ml
respectively.
Other data
| Title | Fabrication of sustainable hydrogels-based chitosan Schiff base and their potential applications | Authors | Kandile, Nadia ; Taghreed H. Abdalla; Abir S. Nasr; Ghada Bassioni; David R. Harding | Keywords | Chitosan;Isonicotinic aldehyde;Epichlorohydrin;Nanohydrogel;Biological activity;Metal removal;Ionotropic gelation | Issue Date | 26-Oct-2021 | Publisher | Elsevier | Journal | Arabian Journal of Chemistry | Volume | 15 | Issue | 103511 | Start page | 1 | End page | 14 | DOI | https://doi.org/10.1016/j.arabjc.2021.103511 |
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