Differential Signaling Pathways in Medulloblastoma: Nano-biomedicine Targeting Non-coding Epigenetics to Improve Current and Future Therapeutics

Sokolov, Daniil; Sharda, Neha; Banerjee, Aindrila; Denisenko, Kseniia; Basalious, Emad B; Shukla, Hem; Waddell, Jaylyn; Prof. Hamdy, Nadia M.; Banerjee, Aditi;

Abstract


Medulloblastomas (MDB) are malignant, aggressive brain tumors that primarily affect children. The survival rate for children under 14 is approximately 72%, while for ages 15 to 39, it is around 78%. A growing body of evidence suggests that dysregulation of signaling mechanisms and noncoding RNA epigenetics play a pivotal role in this disease.


Other data

Title Differential Signaling Pathways in Medulloblastoma: Nano-biomedicine Targeting Non-coding Epigenetics to Improve Current and Future Therapeutics
Authors Sokolov, Daniil; Sharda, Neha; Banerjee, Aindrila; Denisenko, Kseniia; Basalious, Emad B; Shukla, Hem; Waddell, Jaylyn; Prof. Hamdy, Nadia M. ; Banerjee, Aditi
Keywords Medulloblastoma (MDB); disease-hallmarks; epigenetics; in silico; nanomedicine; nanoparticles.; nanotechnology; ncRNA; signaling mechanisms; targeted therapies
Issue Date 2024
Journal Current pharmaceutical design 
ISSN 13816128
DOI 10.2174/0113816128277350231219062154
PubMed ID 38151840
Scopus ID 2-s2.0-85182858005

Recommend this item

Similar Items from Core Recommender Database

Google ScholarTM

Check



Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.