Monocytes subsets altered distribution and dysregulated plasma hsa-miR-21-5p and hsa-miR-155-5p in HCV-linked liver cirrhosis progression to hepatocellular carcinoma
Hammad, Reham; Eldosoky, Mona A; Elmadbouly, Asmaa A; Aglan, Reda Badr; AbdelHamid, Sherihan G; Zaky, Samy; Ali, Elham; Abd El Hakam, Fatma El-Zahraa; Mosaad, Alshaimaa M; Abdelmageed, Neamat A; Kotb, Fatma M; Kotb, Hend G; Hady, Ahmed A; Abo-Elkheir, Omaima I; Kujumdshiev, Sandy; Sack, Ulrich; Lambert, Claude; Prof. Hamdy, Nadia M.;
Abstract
The authors aim to investigate the altered monocytes subsets distribution in liver cirrhosis (LC) and subsequent hepatocellular carcinoma (HCC) in association with the expression level of plasma Homo sapiens (has)-miR-21-5p and hsa-miR-155-5p. A step toward non-protein coding (nc) RNA precision medicine based on the immune perturbation manifested as altered monocytes distribution, on top of LC and HCC.
Other data
| Title | Monocytes subsets altered distribution and dysregulated plasma hsa-miR-21-5p and hsa-miR-155-5p in HCV-linked liver cirrhosis progression to hepatocellular carcinoma | Authors | Hammad, Reham; Eldosoky, Mona A; Elmadbouly, Asmaa A; Aglan, Reda Badr; AbdelHamid, Sherihan G; Zaky, Samy; Ali, Elham; Abd El Hakam, Fatma El-Zahraa; Mosaad, Alshaimaa M; Abdelmageed, Neamat A; Kotb, Fatma M; Kotb, Hend G; Hady, Ahmed A; Abo-Elkheir, Omaima I; Kujumdshiev, Sandy; Sack, Ulrich; Lambert, Claude; Prof. Hamdy, Nadia M. | Keywords | HCC; In silico analysis; Liver cirrhosis; Monocyte subsets; hsa-miR-155-5p; hsa-miR-21-5p | Issue Date | Nov-2023 | Journal | Journal of cancer research and clinical oncology | ISSN | 01715216 | DOI | 10.1007/s00432-023-05313-w | PubMed ID | 37639012 | Scopus ID | 2-s2.0-85168904619 |
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