Beclin-1 and hypoxia-inducible factor-1α genes expression: Potential biomarkers in acute leukemia patients

Prof. Hamdy, Nadia M.; Hegab, Hany M; El-Mesallamy, Hala O; Radwan, Sara;

Abstract


Beclin-1, an important autophagic gene, and hypoxia-inducible factor-1α (HIF-1α), the master regulator of the hypoxic response, are reported in several human cancers. However, their expressions in acute leukemia haven't yet been well investigated.


Other data

Title Beclin-1 and hypoxia-inducible factor-1α genes expression: Potential biomarkers in acute leukemia patients
Authors Prof. Hamdy, Nadia M. ; Hegab, Hany M; El-Mesallamy, Hala O; Radwan, Sara 
Keywords Acute leukemia; Beclin-1; HIF-1α; MAP1LC3B; autophagy
Issue Date 18-Mar-2016
Publisher IOS PRESS
Journal Cancer biomarkers : section A of Disease markers 
Volume 16
Issue 4
Start page 619
End page 629
ISSN 15740153
DOI 10.3233/CBM-160603
PubMed ID 27002764
Scopus ID 2-s2.0-84965017134
Web of science ID WOS:000374755400003

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