Genotype screening of APLN rs3115757 variant in Egyptian women population reveals an association with obesity and insulin resistance
Aboouf, Mostafa A; Prof. Hamdy, Nadia M.; Amin, Ashraf I; El-Mesallamy, Hala O;
Abstract
Apelin is one of adipokines that plays a pivotal role in energy metabolism, insulin sensitivity and vascular integrity. A definite genetic variant of apelin gene (APLN), rs3115757, was recently introduced to potentially influence apelin expression in adipocytes. The aim of our study was to explore the sights of a potential association of this functional variant with obesity traits, insulin resistance indices as well as type 2 diabetes mellitus (T2DM) prevalence.
Other data
| Title | Genotype screening of APLN rs3115757 variant in Egyptian women population reveals an association with obesity and insulin resistance | Authors | Aboouf, Mostafa A; Prof. Hamdy, Nadia M. ; Amin, Ashraf I; El-Mesallamy, Hala O | Keywords | Apelin; Genotyping;Obesity; T2DM;Metabolic syndrom;Insulin resistance | Issue Date | Jul-2015 | Journal | Diabetes research and clinical practice | Volume | 109 | Issue | 1 | ISSN | 01688227 | DOI | 10.1016/j.diabres.2015.05.016 | PubMed ID | 26025696 | Scopus ID | 2-s2.0-84930820102 |
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