Clinical value of circulating lipocalins and insulin-like growth factor axis in pancreatic cancer diagnosis
El-Mesallamy, Hala O; Prof. Hamdy, Nadia M.; Zaghloul, Ashraf S; Sallam, Alaliaa M;
Abstract
Early diagnosis of pancreatic cancer (PC) in diabetic patients is difficult owing to late presentation of symptoms. Hence, finding a marker to identify cancer stage early would be useful to improve survival. We aimed to determine levels of serum retinol binding protein 4 (RBP-4), neutrophil gelatinase-associated lipocalin (NGAL), insulin-like growth factor I (IGF-I), and its binding protein 3 (IGFBP-3) in patients with PC with preexisting type 2 diabetes. Moreover, we assessed their clinical usefulness in PC diagnosis and their association with tumor severity.
Other data
| Title | Clinical value of circulating lipocalins and insulin-like growth factor axis in pancreatic cancer diagnosis | Authors | El-Mesallamy, Hala O; Prof. Hamdy, Nadia M. ; Zaghloul, Ashraf S; Sallam, Alaliaa M | Keywords | IGF-I;insulin resistance;NGAL;pancreatic cancer;RBP-4 | Issue Date | Jan-2013 | Journal | Pancreas | Volume | 42 | Issue | 1 | Start page | 149 | End page | 154 | ISSN | 08853177 | DOI | 10.1097/MPA.0b013e3182550d9d | PubMed ID | 22617715 | Scopus ID | 2-s2.0-84872083433 |
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