Diagnostic Value of Urinary Molecular Markers in Bladder Cancer
Eissa, Sanaa; Swellam, Menha; el-Mosallamy, Hala; Prof. Hamdy, Nadia M.; Kamel, Khaled; Zaglol, A S; Khafagy, M M; el-Ahmady, O; Mourad, Mohamed Sherif;
Abstract
In an attempt to find a more sensitive and specific non-invasive diagnostic assay for the detection of bladder cancer cells, the authors assayed the exfoliated cells from patient's voided urine and bladder washing fluids for the presence of telomerase, an enzyme that maintains a cell's chromosomal length, metalloproteinase-9 (MMP-9), which has been associated with tumor cell invasion and metastasis. Their results were compared with both voided urine cytology (VUC) and bladder wash cytology (BWC) for the detection of bladder cancer cells.
Other data
| Title | Diagnostic Value of Urinary Molecular Markers in Bladder Cancer | Authors | Eissa, Sanaa ; Swellam, Menha; el-Mosallamy, Hala; Prof. Hamdy, Nadia M. ; Kamel, Khaled; Zaglol, A S; Khafagy, M M; el-Ahmady, O; Mourad, Mohamed Sherif | Keywords | Bilharziasis;Bladder cancer (BC);Bladder wash (BW);MMP-9;Telomerase activity;Urine cytology (UC) | Issue Date | 2003 | Journal | Anticancer research | ISSN | 0250-7005 | PubMed ID | 14666650 | Scopus ID | 2-s2.0-0142243281 |
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