HPLC-ESI/MS-MS characterization of compounds in Dolomiaea costus extract and evaluation of cytotoxic and antiviral properties: molecular mechanisms underlying apoptosis-inducing effect on breast cancer
El-Nashar, Heba A. S.; Fattah, Nasra F Abdel; Loutfy, Samah A; Abdel-Salam, Ibrahim M; Eldahshan, Omayma;
Abstract
Dolomiaea costus (syn: Saussurea costus; Family Asteraceae) occupies an important place in the traditional Chinese medicinal plants and is prescribed for a wide range of disorders. The current study aimed to tentatively identify the phytoconstituents of D. costus extract and to explore antiproliferative activity against human breast cancer cells and its possible apoptotic mechanism along with antiviral activity against human adenovirus 5 (Adv-5).
Other data
| Title | HPLC-ESI/MS-MS characterization of compounds in Dolomiaea costus extract and evaluation of cytotoxic and antiviral properties: molecular mechanisms underlying apoptosis-inducing effect on breast cancer | Authors | El-Nashar, Heba A. S. ; Fattah, Nasra F Abdel; Loutfy, Samah A; Abdel-Salam, Ibrahim M; Eldahshan, Omayma | Keywords | Antiviral;Apoptosis;Asteraceae;Breast cancer;Flavonoids;Saussurea costus | Issue Date | 6-Oct-2023 | Journal | BMC complementary medicine and therapies | ISSN | 2662-7671 | DOI | 10.1186/s12906-023-04164-9 | PubMed ID | 37803435 | Scopus ID | 2-s2.0-85173376840 |
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