Protective effect of acrocarpus fraxinifolius extract against hepatic fibrosis induced by Gamma irradiation and carbon tetrachloride in albino rats

El-Shawi, Omama E; El-Nashar, Heba A. S.; Abd El-Rahman, Sahar S; Eldahshan, Omayma;

Abstract


Liver fibrosis is considered as one of the ultimate outcomes of chronic liver disorders, characterized by outrageous cell proliferation and abnormal deposition of extracellular matrix, resulting in sever pathological distortions in the architecture and performance of liver tissues. The present study aimed to investigate the protective properties of aqueous methanol extract of Acrocarpus fraxinifolius leaves (AFL) against liver fibrosis induced by dual toxicity of γ-irradiation and carbon tetrachloride (CCl4) in rats.


Other data

Title Protective effect of acrocarpus fraxinifolius extract against hepatic fibrosis induced by Gamma irradiation and carbon tetrachloride in albino rats
Authors El-Shawi, Omama E; El-Nashar, Heba A. S. ; Abd El-Rahman, Sahar S; Eldahshan, Omayma 
Keywords Acrocarpus fraxinifolius;Liver;carbon tetrachloride;fibrosis;metalloproteinase;radiation
Issue Date 2023
Journal International journal of radiation biology 
Volume 99
Issue 2
Start page 270
End page 280
ISSN 0955-3002
DOI 10.1080/09553002.2022.2087926
PubMed ID 35675546
Scopus ID 2-s2.0-85132772736

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