A new antidiabetic and anti-inflammatory biflavonoid from Schinus polygama (Cav.) Cabrera leaves

El-Nashar, Heba A. S.; Mostafa, Nada M; Eldahshan, Omayma;

Abstract


A new biflavonoid, luteolin-(6→8'')-apigenin was isolated from 80% methanol extract of Schinus polygama (Cav.) Cabrera leaves (Anacardiaceae). The structure was elucidated by 1D and 2D-NMR spectroscopic data. This compound exhibited in vitro antidiabetic effect via α-amylase assay. Furthermore, it possesses anti-inflammatory activity through membrane stabilization effect on erythrocytes.


Other data

Title A new antidiabetic and anti-inflammatory biflavonoid from Schinus polygama (Cav.) Cabrera leaves
Authors El-Nashar, Heba A. S. ; Mostafa, Nada M; Eldahshan, Omayma 
Keywords Schinus polygama;amylase;anti-inflammatory;biflavonoid;membrane stabilization
Issue Date Mar-2022
Journal Natural Product Research 
Volume 36
Issue 5
Start page 1182
End page 1190
ISSN 14786419
DOI 10.1080/14786419.2020.1864365
PubMed ID 33356557
Scopus ID 2-s2.0-85098540567

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