Crevicular Fluid Growth Factors Release Profile Following the Use of Platelet-Rich Fibrin and Plasma Rich Growth Factors in Treating Periodontal Intrabony Defects: A Randomized Clinical Trial

Gamal, Ahmed; Abdel Ghaffar, Khaled A; Alghezwy, Osama A;

Abstract


The open, usually contaminated nature of periodontal defects could negatively affect availability and activity of platelet concentrate-suggested growth factors (GF). The aim of this study is to test this hypothesis and investigate concentrations of: 1) vascular endothelial growth factor (VEGF) and 2) platelet-derived growth factor (PDGF-BB) in gingival crevicular fluid (GCF) from localized intrabony defects treated with platelets rich in growth factors (PRGF) or platelet-rich fibrin (PRF) compared with a control xenograft defect filling.


Other data

Title Crevicular Fluid Growth Factors Release Profile Following the Use of Platelet-Rich Fibrin and Plasma Rich Growth Factors in Treating Periodontal Intrabony Defects: A Randomized Clinical Trial
Authors Gamal, Ahmed ; Abdel Ghaffar, Khaled A; Alghezwy, Osama A
Keywords Blood platelets; intercellular signaling peptides and proteins;tissue engineering;periodontal regeneration
Issue Date Jun-2016
Journal Journal of periodontology 
ISSN 0022-3492
1943-3670
DOI 10.1902/jop.2016.150314
PubMed ID 26876351
Scopus ID 2-s2.0-84971280170

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