A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis
Samer S. El-Kamary; Michelle D. Shardell; Soheir Ismail; Mohamed El-Ateek; Mohamed Metwally; Nabiel Mikhail; Amr Mousa; Aboul Fotouh, Aisha; Mohamed El-Kassas; Gamal Esmat; G. Thomas Strickland; Mohamed Hashem; abdelgawad, mohammed;
Abstract
Milk thistle or its purified extract, silymarin (Silybum marianum), is widely used in treating acute or chronic hepatitis. Although silymarin is hepatoprotective in animal experiments and some human hepatotoxic exposures, its efficacy in ameliorating the symptoms of acute clinical hepatitis remains inconclusive. In this study, our purpose was to determine whether silymarin improves symptoms, signs and laboratory test results in patients with acute clinical hepatitis, regardless of etiology.
Other data
| Title | A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis | Authors | Samer S. El-Kamary; Michelle D. Shardell; Soheir Ismail; Mohamed El-Ateek; Mohamed Metwally; Nabiel Mikhail; Amr Mousa; Aboul Fotouh, Aisha ; Mohamed El-Kassas; Gamal Esmat; G. Thomas Strickland; Mohamed Hashem; abdelgawad, mohammed | Keywords | Egypt | Hepatitis;Milk thistle;Silymarin;Randomized controlled trial | Issue Date | 2009 | Journal | Phytomedicine | ISSN | 0944-7113 | DOI | 10.1016/j.phymed.2009.02.002 | PubMed ID | 19303273 | Scopus ID | 2-s2.0-64649096872 |
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