Cerebral blood flow and serum neuron-specific enolase in early-onset neonatal sepsis

M Sami El Shimi; El-Raggal, Nehal M; El-Farrash, Rania A; Shaaban, Hebatallah A; Mohamed, Hanan E; Barakat, Noha M; Farag, Ahmed S; El Zohiery, Abeer K; Shaaban, Menat Allah A; Salama, Dina H;

Abstract


Sepsis leads to systemic inflammatory response with cerebral blood flow (CBF) alteration and blood-brain barrier disruption that contribute to sepsis-associated encephalopathy (SAE). We aimed to evaluate cord blood neuron-specific enolase (cNSE) and CBF in early-onset neonatal sepsis (EONS) as predictors of SAE and to define short-term neurodevelopmental outcomes among survivors.


Other data

Title Cerebral blood flow and serum neuron-specific enolase in early-onset neonatal sepsis
Authors M Sami El Shimi ; El-Raggal, Nehal M; El-Farrash, Rania A; Shaaban, Hebatallah A; Mohamed, Hanan E; Barakat, Noha M; Farag, Ahmed S; El Zohiery, Abeer K; Shaaban, Menat Allah A; Salama, Dina H
Keywords EARLY-DIAGNOSIS; SEPTIC SHOCK; ENCEPHALOPATHY; CHILDREN; CHORIOAMNIONITIS; DYSFUNCTION; MANAGEMENT; INFANTS; DAMAGE
Issue Date 2018
Publisher NATURE PUBLISHING GROUP
Journal Pediatric research 
ISSN 0031-3998
DOI 10.1038/s41390-018-0062-4
PubMed ID 29907848
Scopus ID 2-s2.0-85048579052
Web of science ID WOS:000449496600020

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