An Eco-Friendly Synthesis of Some Novel Chromene-Based Heterocyclic Compounds of Biological Interest
Abass, Eman; F. M. Abdelrazekc; A. F. El-Farargyb; E. M. Nassara;
Abstract
Abstract—The target chromonylchalcone 3-(3-(4-oxo-4H-chromen-3-yl)-acryloyl)-2H-chromen-2-one
was synthesized by reacting 3-acetylcoumarin with 3-formylchromone. The chromonylchalcone was reacted
with active methylene reagents, thiourea, hydrazines, aromatic amines, and sodium azide to afford new heterocyclic
compounds. The newly prepared compounds were screened for their anti-microbial and antiinflammatory
activities.
was synthesized by reacting 3-acetylcoumarin with 3-formylchromone. The chromonylchalcone was reacted
with active methylene reagents, thiourea, hydrazines, aromatic amines, and sodium azide to afford new heterocyclic
compounds. The newly prepared compounds were screened for their anti-microbial and antiinflammatory
activities.
Other data
| Title | An Eco-Friendly Synthesis of Some Novel Chromene-Based Heterocyclic Compounds of Biological Interest | Authors | Abass, Eman ; F. M. Abdelrazekc; A. F. El-Farargyb; E. M. Nassara | Issue Date | 19-Oct-2019 | Publisher | Springer | Journal | RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY | Volume | 46 | Issue | 4 | DOI | 10.1134/S1068162020040135 |
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