Managing Diabetes and Liver Disease Association Guidelines (Consensus) Development.

Abstract

The issue of association between DM and liver disease is growing all over the world. The association between DM and liver disease has relevance to diabetologists, hepatologists, and primary care physicians. Association between these two common diseases (statistical association) is well known, in addition, liver disease associated with DM can be divided into three groups: 1- Liver disease occurring as a consequence of DM : Most important is NAFLD. Vicious circle appears linking fatty liver to DM and DM to progressive liver injury. 2- DM occurring as a complication of liver disease: Hepatogenous diabetes (HD) caused by liver cirrhosis and chronic hepatitis c. 3- Liver disease occurring coincidentally with DM. The Criteria for diagnosis of DM associating liver disease are the same as for the ordinary primary diabetes, taking into consideration the clinical & laboratory differences from the primary T2 DM. In patients with compensated liver disease, HbA1c may be suitable for long term glycemic control. In those with de-compensated condition, an alternative parameter as fructosamine or frequent glucose monitoring is more suitable.