Microwave-assisted synthesis and antimicrobial activities of flavonoid derivatives

Sherif B. Abdel Ghani;

Abstract


Eleven flavonoid derivatives were synthesised using a modified Baker–Venkataraman rearrangement, and subsequent
microwave-assisted closure of the heterocyclic ring. All of the synthetic compounds displayed antifungal activity against Aspergillus
niger and Fusarium oxysporium, and two of the synthetic flavonoid analogues exhibited significant activity against methicillin-resis
tant Staphylococcus aureus.


Other data

Title Microwave-assisted synthesis and antimicrobial activities of flavonoid derivatives
Authors Sherif B. Abdel Ghani 
Issue Date 28-Nov-2007
Publisher Bioorganic & Medicinal Chemistry Letters
Journal Bioorganic & Medicinal Chemistry Letters 
DOI doi:10.1016/j.bmcl.2007.11.081

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