Gingival-derived mesenchymal stem cell therapy regenerated the radiated salivary glands: functional and histological evidence in murine model
Zayed, Hagar M; Kheir El Din, Nevine H; Abu-Seida, Ashraf M; Abo Zeid, Asmaa A; Ezzatt, Ola;
Abstract
Radiotherapy in head and neck cancer management causes degeneration of the salivary glands (SG). This study was designed to determine the potential of gingival mesenchymal stem cells (GMSCs) as a cell-based therapy to regenerate irradiated parotid SG tissues and restore their function using a murine model.
Other data
| Title | Gingival-derived mesenchymal stem cell therapy regenerated the radiated salivary glands: functional and histological evidence in murine model | Authors | Zayed, Hagar M; Kheir El Din, Nevine H; Abu-Seida, Ashraf M; Abo Zeid, Asmaa A; Ezzatt, Ola | Keywords | Anti-proliferating cell nuclear antigen; Apop-Tag Peroxidase; Guinea pigs; Oral derived stem cells; Xerostomia | Issue Date | 16-Feb-2024 | Journal | Stem cell research & therapy | ISSN | 1757-6512 | DOI | 10.1186/s13287-024-03659-7 | PubMed ID | 38365799 | Scopus ID | 2-s2.0-85185396781 |
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