Diagnostic Performance of ChatGPT-4o and DeepSeek-3 Differential Diagnosis of Complex Oral Lesions: A Multimodal Imaging and Case Difficulty Analysis
Hassanein, Fatma E A; El Barbary, Ahmed; Hussein, Radwa R; Ahmed, Yousra; El-Guindy, Jylan; Sarhan, Susan; Abou-Bakr, Asmaa;
Abstract
AI models like ChatGPT-4o and DeepSeek-3 show diagnostic promise, but their reliability in complex, image-based oral lesions remains unclear. This study aimed to evaluate and compare the diagnostic accuracy of ChatGPT-4o and DeepSeek-3 despite their differing modalities against oral medicine (OM) experts across varied lesion types and case difficulty levels.
Other data
| Title | Diagnostic Performance of ChatGPT-4o and DeepSeek-3 Differential Diagnosis of Complex Oral Lesions: A Multimodal Imaging and Case Difficulty Analysis | Authors | Hassanein, Fatma E A; El Barbary, Ahmed; Hussein, Radwa R; Ahmed, Yousra; El-Guindy, Jylan; Sarhan, Susan ; Abou-Bakr, Asmaa | Keywords | ChatGPT‐4; DeepSeek‐3; artificial intelligence; diagnostic accuracy; differential diagnosis; oral lesions | Issue Date | Dec-2025 | Journal | Oral diseases | ISSN | 1354523X | DOI | 10.1111/odi.70007 | PubMed ID | 40589366 | Scopus ID | 2-s2.0-105009522786 |
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