The effect of 12 weeks carnosine supplementation on renal functional integrity and oxidative stress in pediatric patients with diabetic nephropathy: a randomized placebo-controlled trial
Elbarbary, Nancy Samir; Ismail, Eman Abdel Rahman; El-Naggar, Abdel Rahman; Hamouda, Mahitab Hany; elhamamsy, manal;
Abstract
Oxidative stress is a significant contributor to the pathogenesis of diabetic nephropathy. Carnosine is a natural radical oxygen species scavenger. We investigated the effect of carnosine as an adjuvant therapy on urinary albumin excretion (UAE), the tubular damage marker alpha 1-microglobulin (A1M), and oxidative stress in pediatric patients with type 1 diabetes and nephropathy.
Other data
| Title | The effect of 12 weeks carnosine supplementation on renal functional integrity and oxidative stress in pediatric patients with diabetic nephropathy: a randomized placebo-controlled trial | Authors | Elbarbary, Nancy Samir; Ismail, Eman Abdel Rahman ; El-Naggar, Abdel Rahman; Hamouda, Mahitab Hany; elhamamsy, manal | Keywords | alpha-1 microglobulin; carnosine; diabetic nephropathy; oxidative stress; type 1 diabetes | Issue Date | May-2018 | Journal | Pediatric diabetes | ISSN | 1399543X | DOI | 10.1111/pedi.12564 | PubMed ID | 28744992 | Scopus ID | 2-s2.0-85045743591 |
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